Limitations of In-line Filters
In-line filters can be highly effective at removing waterborne pathogens like Legionella and Pseudomonas from the incoming water supply. However, compared to traditional POU filters, one critical limitation is the risk of post-filtration (after-filter) microbial contamination in the pipework between the filter and the outlet.

When an in-line filter is installed upstream of the final outlet (e.g., within ceiling voids or behind walls), the water still travels through a short length of pipework before reaching the user. This downstream section is unprotected by the filter and can become colonized with bacteria over time – especially if conditions promote biofilm formation, such as:
- Stagnation or low-use outlets, which allow warm water to sit in the pipe
- Inadequate flow velocities, leading to sediment accumulation and microbial adhesion
- Poor materials, such as flexible hoses or rough-surfaced pipes, are more prone to biofilm
- Infrequent flushing, which fails to clear microbial buildup
The pathogens growing in this after-filter pipework can be released intermittently during use, bypassing the filtration barrier and exposing patients. To mitigate this, it is essential to install the in-line filter as close to the outlet as possible, minimizing the length of unprotected pipe.
Where short connections are unavoidable, the use of smooth-bore, rigid, or antimicrobial pipe materials can reduce biofilm risk. Regular thermal or chemical disinfection of downstream pipework should also be considered, especially in areas with stagnant water or infrequent use. Daily flushing routines and careful configuration of thermostatic mixing valves (ideally located before the filter) further support control.